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ALS Clinical Care and the Future of Research

December 11, 2021 by Rhema Jones Leave a Comment

On November 15 2021, ALS Texas was joined by Neurologists and Clinic Directors, Dr. Jeffrey Tramonte and Dr. Stanley Appel for a special panel discussion. During this exciting presentation, they discussed the growth of multidisciplinary care and where the momentum is in ALS research. Keep reading for a recap of this exciting panel!

Introducing Our Special Guests

Dr. Jeffrey Tramonte is the clinic director at the Emory Bellard ALS Clinic at Baylor Scott & White Health. He has over 15 years of experience working with ALS patients. In 2011, he started the ALS Clinic after treating famous football coach, Emory Bellard, who had ALS. With the support of Bellard and his community, funds were raised to begin the clinic. This year marks a decade of service to Texans with ALS for the Emory Bellard ALS Clinic.

The ALS Clinic at Houston Methodist began in 1982. Dr. Stanley Appel shared it was the first ALS clinic in the world to offer multidisciplinary care. The clinic became an ALS Association Certified Treatment Center in 2016, and next year, the clinic will celebrate its 40th anniversary. “We’re still going, and we’re still committed to doing everything we can to help our patients,” he shared.

These clinics not only provide excellent care to Texans with ALS, but they also bring hope through research.

Research Updates from Houston Methodist

Dr. Appel is known as an innovator in the ALS research field hosting many clinical trials at his clinic. Most notable, he’s discovered a potential treatment that could halt the progression of ALS using regulatory T Cells, aka Tregs. He shared an update on the study during the panel

The latest study for Treg was powered to give them critical answers to the effectiveness of this treatment. But the COVID-19 pandemic has created some delays. Amid these difficulties, Dr. Appel is pressing forward.

“The data looks very promising, very exciting, and we’re really hopefully that in the future in a much larger trial not affected by COVID-19 that we can be successful in bringing new  therapy to our patients.”

Houston Methodist not only hosts the T-reg Study but is also a site for the the HEALEY ALS Platform Trial. The platform allows for multiple drug treatments to be tested with one placebo group. This means more patients can participate and there’s a bigger chance they receive an experimental drug and not a placebo. Those living with ALS play an integral part in making these research breakthroughs. Without clinical trials, there’s no way to know the efficacy of a drug.

Research Goes Beyond Clinical Trials

There are often accessibility issues for patients who want to participate in clinical trials. “There’s not enough of them and there’s not enough places to go to get access to the research,” Dr. Tramonte noted. Unfortunately, there are also cases where patients are ineligible to join a trial, but they can still contribute to critical research.

One way Texans with ALS can get involved with research without participating in clinical trials is through the National ALS Registry. This database is the largest ALS research project ever created. It’s also the only population-based registry in the U.S. that provides crucial information to scientists about the disease. This information plays a crucial role in supporting ALS research across the entire country!

Clinical Advancements Over the Years

ALS multidisciplinary care has come a long way since it’s development in the 1980’s. Even in the last decade, we’ve seen massive improvements to the quality of care for those living with ALS. Dr. Tramonte notes that the biggest improvement he’s observed is in feeding tube placement. A decade ago, ALS patients had to do the procedure while their lungs were strong enough to handle the general anesthesia.

“The problem is, is that for a good number of our patients they had really intact chewing, swallowing, didn’t have any nutritional needs, but the lung function was declining.” This would leave many patients with a feeding tube long before they needed it. Today, the procedure can be done under local anesthesia, allowing those with ALS to wait longer before having a feeding tube placed.

Dr. Appel believes that the greatest advancement is in multidisciplinary care itself. “There’s no question that our patients are living longer with better quality,” he shared. He attributes this to the improvements in breathing treatments, like the Trilogy, and nutritional advancements through feeding tubes.

Challenges for Multidisciplinary Clinics

“The biggest challenge for us is institutional buy-in,” Dr. Tramonte shared. “Convincing hospital administrators, healthcare system administrators, why this venture is important.” From a business standpoint, ALS Clinics don’t benefit hospital systems, but they are so important. Clinic directors across Texas know that it’s crucial to share the life-saving impact of these clinics to their administrators.

ALS Texas is dedicated to funding these life-saving multidisciplinary clinics to give Texans with ALS access to excellent care. This is made possible through the support of our community! Despite the challenges of running a clinic, both neurologists have high hopes for the future of their clinics.

Dr. Appel and Dr. Tramonte were asked what they would offer in a world with unlimited resources. Both neurologists emphasized the importance of mental health. They wish to expand their clinics to cover those services through hiring more social workers and psychologists.

“Going through what to expect: the anticipation, the uncertainty, the anxiety, the depression—it’s profound. And not only does it affect the patients right? But it affects families, their caregivers. If we could provide mental health services, that would be fantastic.” Dr. Tramonte

The Future Role of Telemedicine

In the last year, telemedicine has expanded across the country. The concept existed long before the pandemic, but it was crucial in keeping patients connected to their care teams. But what does the future role of telemedicine look like?

Both neurologists agree, there are pros and cons to telemedicine. For some exams and treatments, they require in-person contact. However, there is no doubt that telemedicine significantly expands access to multidisciplinary care. As ALS progresses, it becomes more difficult for patients to travel, so digital visits keep those patients connected.

The approach changes from patient to patient, and doctor to doctor. For Dr. Tramonte’s clinic, it hasn’t met the needs of his patients, but he’s interested to seeing where integrations could improve care. Dr. Appel foresees telemedicine becoming an integral part of neurology in the future. Advancements in smartphones and other technologies opens the door to more possibilities.

What’s Next for ALS Clinics

Dr. Jeffrey Tramonte and Dr. Stanley Appel are eager to share their passion and knowledge about ALS with our community. There’s no doubt that the future of multidisciplinary care looks bright. From expansions to access, to extensions of services, more Texans with ALS are receiving the quality care they need.

To hear more from Dr. Tramonte and Dr. Appel about ALS clinical care and the future of research, watch the full event below!

Find a Multidisciplinary ALS Clinic


Donate to Support ALS Clinics

Filed Under: Research Tagged With: als clinics, ALS Research, clinical trial

Advancing Research: The HEALEY ALS Platform Trial

August 16, 2021 by Catherine Nodurft Leave a Comment

In 2020, the ALS Association, in partnership with Massachusetts General Hospital, launched an innovative approach to research, the HEALEY ALS Platform Trial. In most clinical trials, a single drug is tested, and participants cannot be enrolled in more than one trial at a time. The HEALEY ALS Platform Trial enables us to test multiple proposed drug treatments at once. This is a model that has been successful in cancer research. It accelerates our search for effective treatments for people living with ALS by allowing investigators to test more drugs, increase patient access to trials, and reduce costs by quickly and efficiently evaluating the effectiveness of multiple therapies. There are now 54 test sites nationwide, three of which are in Texas.

Texas Neurology was one of the first five initial sites for the new model. “This is big. I’ve been doing trials since the early nineties. The average trial takes 8 years. Going through platform methodology shortens it to 2-3 years,” states Dr. Daragh Heitzman, clinical director at Texas Neurology. Dr. Heitzman was recently appointed to the HEALEY ALS Platform Trial Executive Committee, as the first physician investigator to join an elite group of scientists.

“What’s different about this trial is that the placebo group is being shared for all five drugs, such that the number of participants who actually get a drug is dramatically increased. So, it’s a lot quicker to get to an answer, more patients are getting drugs, and less getting a placebo.”

Trial participants will have the option to continue treatment for at least a year, and if the drug shows promise during the six-month trial, the FDA could potentially fast-track its approval, getting a crucial treatment to people living with ALS.

Texas HEALEY ALS Platform Trial Sites

  • The ALS Clinic at Texas Neurology in Dallas
  • Houston Methodist ALS Clinic
  • The ALS Clinic at UT Health San Antonio

Read more about Dr. Heitzman and the clinic at Texas Neurology

How ALS Patients Can Help with Research

Filed Under: Research, Research News Tagged With: ALS drug, ALS Research, ALS treatment

ALS Association Continues to Put Pressure on the FDA Following the We Can’t Wait Action Meeting

June 24, 2021 by Rhema Jones Leave a Comment

One month ago on May 25, 2021, representatives from the FDA joined a We Can’t Wait Action Meeting. During this meeting, eight ALS advocates from across the US shared their personal experience with the disease to highlight why those with ALS need expedited access to experimental therapies.

Following the We Can’t Wait Action Meeting, the ALS Association sent a letter to the FDA that requests the agency to reaffirm their commitment to the 2019 ALS Guidance and provide details regarding how they have implemented the guidance.

The FDA’s Response to the Letter

Dr. Patrizia Cavazzoni, Director of the Center for Drug Evaluation and Research sent a response letter to the ALS Association on June 15, 2021. The letter acknowledges the “burden of ALS for patients, their families and caregivers,” noting there is an “unmet need for treatments” for the disease.

We can also assure you that we are exercising the regulatory flexibility described in FDA’s 2019 guidance for industry titled Amyotrophic Lateral Sclerosis: Developing Drugs for Treatment (ALS Guidance) and we continue to commit to doing so,” Dr. Cavazzoni shared in the letter.

The FDA responded positively to the We Can’t Wait Action Meeting, but the ALS community still has grave concerns. The FDA has not clearly communicated what they are doing to expedite the approval of promising treatments for ALS patients. Yet they allow regulatory flexibility for other disease treatments.

The FDA recently used its regulatory flexibility to approve Aduhelm to treat Alzheimer’s. While this is great news for those living with Alzheimer’s and their loved ones, those living with ALS are left to wonder why the same urgency is not granted to them.

In the letter from the FDA, Dr. Cavazzoni shared that they are “committed to exercising [the guidance] when appropriate.” However, the agency does not appear to make any of those considerations for AMX0035. The drug met its primary and secondary endpoints in The Phase 2 Trial and is generally safe. Yet the FDA requires another clinical trial.

Health Canada is already working with Amylyx to bring the drug to market for Canadians with ALS in 2021. Yet Americans with ALS will have to wait years to access the drug. That is if the FDA even allows it to hit the market.

How We’re Moving Forward

The ALS Association is deeply committed to expediting the access to promising drug treatments to those living with ALS. We hope to achieve this by:

  1. Continuing to put public pressure on the FDA
  2. Work behind the scenes to expedite change
  3. Seek greater public accountability for the FDA

Read more about this response and how the ALS Association is implementing the above action items here. Our organization will continue to share important updates as they arise as we continue the fight to end ALS. We will not rest until we find a cure!

Read the Full Letter from the FDA

Read the We Cant Wait Action Meeting Summary

Become an ALS Advocate

Filed Under: Advocacy, News, Research Tagged With: advocacy, ALS drug, ALS Research, FDA

We Can’t Wait: ALS Advocates Urge the FDA to Expedite Access to Experimental Therapies

June 3, 2021 by Rhema Jones 1 Comment

The average life expectancy for someone after an ALS diagnosis is only 2 – 5 years. However, the process of developing, testing, and approving new treatments takes far longer. For those living with ALS, time is limited—We Can’t Wait.

On May 25, 2021, representatives from the FDA joined a We Can’t Wait Action Meeting. During this meeting, eight ALS advocates from across the US shared their personal experience with the disease to highlight why those with ALS need expedited access to experimental therapies.

Compelling Testimonials from the ALS Community

John Robinson from Parish, FL, a member of the board of trustees of the ALS Association and retired military veteran of nearly 32 years, was diagnosed with ALS in 2019. ALS not only affects the person with the disease but also their family caregivers. Both he and his wife can no longer serve their communities in the same way because of ALS. “The loss to society of their skills and humanity leaves holes never filled the same way again.”

Sunny Brous, a Texan with ALS, joined the call to share her perspective. Sunny was diagnosed with ALS in 2015 at the young age of 27. For Sunny, access to experimental treatments go beyond extending her own life. “Expanded access is how I can contribute to finding a cure for ALS. It takes my love for others and makes it a quantifiable action combining research and science and my dedication to the greatest good of people living with ALS.”

Sandy Morris, from Truckee, CA played a recorded message. She tearfully shared how many of her friends with ALS died waiting for access to life saving drug treatments. “Think about how much better it would be if we were able to die trying rather than die waiting,” she shared, urging the FDA to consider how their delays harm those living with ALS. “It’s not within my power to save my life—it’s within yours.”

Troy Fields from Champa Bay, FL was diagnosed with ALS in 2018. He noted how the considerations of benefits versus risk should be put in the hands of those living with ALS. “Because unless it is your own life on the line, you simply do not get it.”

Cari Meystrik from Nashville Tennessee was diagnosed with ALS in 1998 when she was only 28 years old. She has watched hundreds of friends die from this awful disease. “Would I jump to try a drug that might help me live longer of a disease that I am dying from if it has already proven to be sage and well tolerated but isn’t approved yet? Absolutely. Give me that chance.”

Jay Quinlan from New Orleans joined with his wife and caregiver Stephanie. “You have shown through your recent handling approvals for COVID vaccines that flexibility and expediting processes are possible.” He asked the FDA to use the same urgency when it comes to approving drug treatments for those living with ALS.

Tommy May from Pine Bluff, AR was diagnosed with ALS in 2005. Due to slow progressions, he was both unable to participate in clinical tries and frustrated with the lack of access to treatments. He discussed how those living with ALS are desperate for HOPE on their path. “We are not interested in the long-term. We are desperate for the here now.”

Larry Falivena of Apex, NC, has ALS caused by a mutation of the SOD1 gene. The fight for treatment access is not just for himself—it is also for his children. “I’m asking the FDA to help make sure my boys don’t have to worry about ALS.” He shares that even if the opportunity exists for just a small number of patients to have extended time on this earth that they need that chance.

Where Do We Go from Here?

In 2021, the ALS Association is committed to accelerating the development, approval, and access to affective new treatments. We will do this by re-introducing and passing the Accelerating Access to Critical Therapies (ACT) for ALS Act and the Promising Pathway Act, so the FDA is fully equipped to speed ALS trials and drug approvals. We will discuss these matters further during the annual ALS Advocacy Conference in June.

It is our sincere hope that the testimonials of these individuals and those who sent written stories will compel the FDA to make actionable changes for the ALS community. Time is off the essence—We Can’t Wait.

Submit your testimony to the FDA

Register for the Virtual ALS Advocacy Conference

Read Our 2021 Advocacy Priorities

Filed Under: Advocacy, News, Research Tagged With: advocacy, ALS Advocacy, ALS Research, ALS treatment, FDA

Because of You: 2020 in Review

November 18, 2020 by Tanner Hockensmith Leave a Comment

This year our ALS community has come together in new ways, connecting from afar and working together, even when we are physically apart. In the midst of a pandemic your support never ceased. And because of you, we are now serving more people with ALS and their families than ever before.

Because of you, family caregivers are receiving the support and resources they need. Medical equipment is being loaned to people in need and alleviating their financial burden. Youth are sharing their voices and finding strength through shared experiences. ALS clinics are continuing to deliver specialized care and conducting clinical trials. New treatments are on the horizon.

Because of you, our Texas Chapter Events continue to raise crucial funds while moving to socially distanced and virtual fundraisers. And our Walk to Defeat ALS at Home brought Texans together from across the state, allowing us to gather safely even from afar.

This is how your support has made an impact on the lives of Texans with ALS.

Local Care Overview

Our team provides resources and support to people with ALS and their families. Your generosity enables us to continue this critical work, counseling newly diagnosed patients and helping Texans with ALS navigate the disease.

1,004 People with ALS are currently Registered with Our Chapter
(compare to 929 at this time in 2019)

From February to November 2020:

278 New Patients
(compare to 169 at this time in 2019)

1,165 Total Patients Served
(compare to 1,207 in all of 2019)

Learn more about our Local Care Programs.

Equipment Loans

Our Equipment Loan Program provides crucial medical equipment to people with ALS, without charge. COVID-19 impacted this program significantly and due to safety concerns we were unable to access and deliver much of our equipment in our loan closet. We were purchasing new equipment to continue to meet the needs of people with ALS, but saw our funding dwindle rapidly. We asked for your help, and through your support, we were able to get the funding needed to continue this vital program. Now, we’re working with our partners to deliver needed equipment in a safe manner and ensure people with ALS have the equipment needed to navigate their everyday lives.

From February to November 2020:

331 Pieces of Equipment Loaned to People with ALS

If you are a person with ALS or caregiver who needs help with equipment, please contact us.

ALS Multidisciplinary Clinics

In the early days of the pandemic, many of our ALS Multidisciplinary Clinics had to cancel regular clinic days. As time has progressed, each clinic has modified their operations to best serve the safety of their community. Most have now resumed normal operations or offer a combination of in-person and virtual visits. We’ve been working closely with our clinic partners to help keep our ALS community safe and ensure our presence as a resource for Texans with ALS and their families.

We partner with 11 ALS clinics across the state of Texas. You can see the latest update about clinics here.

Staying Connected

Gathering in-person is not an option for our ALS community who are at greater risk to infection during this pandemic. To stay connected we moved all support groups to virtual platforms, which have continued to meet monthly. In addition, we transitioned in-person educational presentations and workshops to virtual platforms and provided statewide access. Seeing an emerging need, we also added a Veterans support group.

From March to November 2020:

120 Virtual Support Groups, Workshops, and Presentations

1,336 People Engaged in Virtual Events

You can view our upcoming virtual events here, and watch recordings of past events.

Community Education

Community support has continued for Texans with ALS and their families. We worked with partners across the state to develop an educational series of presentations and interactive workshops. This included a clinical series, focused on different aspects of the ALS clinic, connecting healthcare professionals with the patients they serve.

View the Clinical Series

New Family Programs

We’ve been listening closely to our ALS community to discover where additional resources are needed. Two big needs have emerged: greater support for caregivers and programs for youth and children. This year we have begun rolling out these virtual programs.

  • Workshops for caregivers to manage stress and tips for self-care
  • Workshops for multiple age groups of youth and children to cope with the diagnosis and care of a loved one
  • Bereavement support group
  • Caregiver morning coffee support group
  • Youth Leadership Council
  • National Family Caregivers Month Series
    • A Husband’s Perspective to Caregiving
    • Wife, Partner, and Caregiver – The Balancing Act
    • Young Caregivers Aren’t Alone

Learn More About our Caregiver Program

Learn More About Our Youth & Children Program

Walk to Defeat ALS at Home

The Walk to Defeat ALS 2020 looked very different this year. Although we were unable to all gather in-person, we still stayed connected. Our Live Opening Ceremony featured teams from across the state and conveyed the incredible energy of our ALS community. Big News: We met our goal of raising $1 million. Thank you to everyone who participated in the Texas Walk to Defeat ALS !

Watch the Texas Walk to Defeat ALS Live Opening Ceremony

Research Progress

Because of you, research is advancing and a potential treatment is on the horizon. In September, the New England Journal of Medicine published the results of a phase 2 trial (known as CENTAUR) of the compound AMX0035, produced by Amylyx, a Massachusetts-based pharmaceutical company. The results of the trial were very promising – people with ALS receiving this drug experienced a significantly slower decline in disease progression and lived an average of six months longer, compared to those on a placebo.

The ALS Association and I AM ALS have issued a petition calling on the drug company and the FDA to make the treatment widely available as soon as possible. To date, the petition has received more than 50,000 signatures.

Advocacy

On November 11, the Senate recommended $40M for the Department of Defense ALS Research Program (double the previous year’s amount) and $10M for the CDC National ALS Registry in their FY2021 appropriations bills. These victories help us better support the ALS community and bring us one step closer to defeating the disease.

Next, we wait for the House and Senate to agree on final funding levels. We’re cheering on our ALS community who are continuing to fight to make this a reality.

Looking to the Future

Because of you, we have a lot to look forward to in the new year. In January, we will launch new support groups for elementary and middle school children, as well as teen and young adult groups. We will also kick-off an educational series for people with ALS who have been newly diagnosed and their families, providing them with the resources needed for their journey. This will include information about current research, multidisciplinary care, employment and insurance, and navigating the disease.

Because of you, we have been able to increase access to support groups, presentations and workshops via virtual platforms. As we continue to navigate the pandemic and look beyond this crisis, virtual programming will continue to be a critical part of our work, enabling us to reach Texans with ALS and their families in all corners of the state. Even when we can safely resume in-person gatherings, we’ll continue to provide a place to virtually connect, learn, and share.

In the face of the pandemic, you made this crucial work possible. Thank you.

Filed Under: Fundraising, News, Research Tagged With: als, ALS Advocacy, ALS Research

ALS Drug Shows Further Promise, Slowing Progression and Increasing Survivability

October 17, 2020 by Catherine Nodurft Leave a Comment

Muscle and Nerve has published the results of the open label extension study of AMX0035, a promising new drug therapy for people with ALS developed by Amylyx. The study showed that people who received the drug lived about 6.5 months longer than people who received the placebo during the trial. This finding is in addition to the findings from the phase 2 trial, showing that people with ALS receiving this drug experienced a significantly slower decline in disease progression, compared to those on a placebo.

As quoted in the New York Times article, Neil Thakur, chief mission officer of the ALS Association, states, “That is a very meaningful benefit for people affected by this devastating, fatal disease.”

These findings further show that the treatment should be made available to people with ALS as soon as possible. We urge the FDA and Amylyx to work together to bring this treatment to market as soon as possible and we stand ready to help ensure that happens. You can help by signing our petition to the FDA and Amylyx at als.org/petition.

Filed Under: Research, Research News Tagged With: ALS Research, Research, research news

ALS Drug Slows Progression, Petition for FDA Approval

September 2, 2020 by Katie Kroncke 4 Comments

The New England Journal of Medicine (NEJM) has published the results of a phase 2 trial (known as CENTAUR) of the compound AMX0035, produced by Amylyx, a Massachusetts-based pharmaceutical company. The results of the trial were very promising – people with ALS receiving this drug experienced a significantly slower decline in disease progression, compared to those on a placebo. Additionally, this drug shows to be safe and well-tolerated indicating a positive benefit and risk consideration for people with ALS.

The ALS Association and I AM ALS have now issued a petition calling on the drug company and the FDA to make the treatment widely available as soon as possible. The ALS Association and I AM ALS are asking that Amylyx and the FDA move with urgency to ensure this drug is a treatment option for all people living with ALS.

Click to expand

The ALS Association committed $750,000 to Amylyx in funding for this research, and $1.4M to the NEALS clinical trial consortium to support the trial. These grants were made possible through the ALS Ice Bucket Challenge. The trial included 137 people with ALS and was conducted across 25 top medical centers through the Northeast ALS (NEALS) consortium. All of the participants enrolled in the trial were diagnosed with sporadic or familial ALS within the previous eight months and had a rapid progression of the disease.

With a typical survival time of between 2 to 5 years, people with ALS cannot wait for the full experimental process of this drug to continue. In light of the substantive data of AMX0035’s effectiveness and safety, it has been requested that the FDA and Amylyx to work together to bring this to people with ALS as soon as possible by approving the drug prior to a Phase 3 trial. To access and sign the petition, visit www.als.org/petition.

Sign the Petition Today!

Filed Under: Research, Research News Tagged With: ALS Research, Research, research news

“Spark Hope For a World Without ALS” – Our 2018 Recap

November 27, 2018 by Jacque Amadi Leave a Comment

In 2018 we set out with the goal to spark hope, ignite action, and inspire others to join us in the fight to create a world without ALS. And it was thanks to our wonderful community that we were able to achieve that goal. Throughout the year we provided patient services, hosted community events, and helped fund life-changing research to find new treatments for this devastating disease.

[Read more…]

Filed Under: Fundraising, Research Tagged With: ALS News, ALS Research, ALS Texas, fundraising, walk to defeat als

Your Support Makes a Real Impact

December 29, 2017 by Tanner Hockensmith Leave a Comment

Our vision at ALS Texas is simple: to create a world without ALS. Everything we do – the services we provide, clinics we support, research we fund, and laws and policies we advocate for – is done to help search for effective treatments and find a cure for ALS.

None of this is possible without your support. Would you support our mission by giving a tax-deductible, year-end donation today?

Donate Now

ALS Texas Mission Impact from ALS Association of Texas on Vimeo.

[Read more…]

Filed Under: Fundraising Tagged With: als, ALS Advocacy, ALS awareness, als clinics, ALS Research, ALS Texas, ALS treatment, clinics, patient services

Letter from the Executive Director: Year in Review

December 26, 2017 by Tanner Hockensmith 1 Comment

Executive Director Tanner Hockensmith and his family

Texas is big, really big. Our friends at Texas Humor stated that “if you drive long enough through Texas, you still might not get all the way through it.” As Texans, we pride ourselves on the sheer size of our great state.

However, its sprawling cities, growing suburbs, and vast rural areas pose a real challenge when we think about access. At ALS Texas, we believe that everyone living with ALS deserves to have access to top-notch clinical care, programs and resources that increase quality of life, clinical research studies, and an ALS community advocating for change.

[Read more…]

Filed Under: News Tagged With: advocacy, als, ALS Advocacy, ALS awareness, als clinics, ALS Research, ALS Texas, ALS treatment, Donate, Lou Gehrig's Disease, national als advocacy day, pals, patient services, Public Policy

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Austin Office 2301 W Anderson Lane, Austin, TX, 78757
Houston Office 4201 Main Street, Suite 200-142, Houston, TX 77002